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Browsing by Subject "fibers"

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    Item type:Article, Access status: Open Access ,
    Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes
    (2024) Moradi, Ahmadreza; Lichawska-Cieslar, Agata; Szukala, Weronika; Jura, Jolanta; Berniak, Krzysztof; Stachewicz, Urszula
    Wydział Inżynierii Metali i Informatyki Przemysłowej
    The challenge of enhancing wound healing and skin regeneration, particularly in conditions like burns and diabetic wounds, necessitates innovative solutions. Cholesterol, often associated with cardiovascular diseases, plays vital roles in cellular functions, maintaining skin integrity and preserving the skin barrier. Here, we explore cholesterol's significance, its influence on keratinocytes, and its potential application in skin regeneration. The study utilizes electrospun polyimide (PI) fibers as a cholesterol carrier model and investigates its impact on HaCaT keratinocytes, marking the first time tracked cholesterol delivery from the scaffold into cells. We demonstrate that an optimal concentration of 0.7 mM cholesterol in the medium enhances cell proliferation, while higher concentrations have negative effects. Cholesterol-enriched scaffolds significantly increase cell proliferation and replicative activity, especially in a 3D culture environment. Moreover, cholesterol influences keratinocyte differentiation, promoting early differentiation while inhibiting late differentiation. These findings suggest that cholesterol-loaded scaffolds can have applications in wound healing by promoting cell growth, regulating differentiation, and potentially accelerating wound closure. Further research in this area will lead to innovative wound management and tissue regeneration strategies.
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    Item type:Article, Access status: Open Access ,
    Flexible and thermally insulating porous materials utilizing hollow double-shell polymer fibers
    (2024) Knapczyk-Korczak, Joanna; Szewczyk, Piotr K.; Berniak, Krzysztof; Marzec, Mateusz M.; Frąc, Maksymilian; Pichór, Waldemar; Stachewicz, Urszula
    Wydział Inżynierii Metali i Informatyki Przemysłowej
    The global climate change is mainly caused by carbon dioxide ($CO_{2}$) emissions. To help reduce $CO_{2}$ emissions and conserve thermal energy, sustainable materials based on flexible thermal insulation are developed to minimize heat flux, drawing inspiration from natural systems such as polar bear hairs. The unique structure of hollow double-shell fibers makes it possible to achieve low thermal conductivity in the material while retaining exceptional elasticity, allowing it to adapt to insulation systems of any shape. The layered system of porous mats reaches a thermal conductivity coefficient of $0.031 W∙m^{−1}∙K^{−1}$ and enables to reduce the heat transfer. The results achieved using scanning thermal microscopy (SThM) correlate with the simulated heat flow in the case of individual fibers. This research study brings new insights into the energy efficiency of domestic environments, thereby addressing the growing demand for sustainable and high-performance insulation materials for saving energy loss and reducing pollution footprint.
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    Item type:Presentation, Access status: Open Access ,
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    Item type:Article, Access status: Open Access ,
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    Item type:Article, Access status: Open Access ,
    Multifunctional, Flexible and Interactive PVDF Fibers with Tunable Conductivity via CNT Coatings for Sensing and Smart Textile Applications
    (2025) Kopacz, Michał; Szewczyk, Piotr K.; Długoń, Elżbieta; Berniak, Krzysztof; Nizioł, Jacek; Jeleń, Piotr; Sitarz, Maciej; Stachewicz, Urszula
    Wydział Inżynierii Metali i Informatyki Przemysłowej
    Integrating electronics into textiles has the potential to revolutionize wearable devices, but achieving conductivity without compromising breathability and flexibility remains a challenge. Electrospun polyvinylidene fluoride (PVDF) fibers offer a porous and flexible scaffold but are inherently insulating. Previous methods for adding conductivity often reduce vapor permeability and mechanical performance. Here, this study reports a two-step fabrication strategy using electrophoretic deposition (EPD) of carbon nanotubes (CNTs) onto electrospun PVDF fibers, resulting in highly conductive (80 $\pm$ 6 $\Omega$), porous, and stretchable mats (elongation of ≈600%). The EPD process enables tunable conductivity while preserving fiber structure and water vapor transmission. The mats achieve significantly lower impedance and enhanced mechanical performance compared to existing coatings. This study demonstrates the use of these composites as sensors capable of detecting pressure, motion, respiration, and temperature. This multifunctionality, combined with scalable fabrication, highlights their potential in smart textiles. These findings open new opportunities for designing wearable sensors that unite functionality, user comfort, and durability.
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    Item type:Thesis, Access status: Restricted ,
    Rusztowania włókniste do regeneracji układu nerwowego
    (Data obrony: 2017-01-23) Brzuchacz, Agnieszka
    Wydział Elektrotechniki, Automatyki, Informatyki i Inżynierii Biomedycznej