Browsing by Subject "skin"

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Access status: Open Access ,
Oil-infused polymer fiber membranes as porous patches for long-term skin hydration and moisturization
(2023) Szewczyk, Piotr K.; Kopacz, Michał; Krysiak, Zuzanna; Stachewicz, Urszula
Skin allergies and diseases, including atopic dermatitis (AD), affect millions worldwide. Current treatments for AD are often expensive, leading to a need for cost-effective solutions. Here, using fiber-based patches to maintain and increase skin hydration is explored, which helps treat eczema and AD. Nanofiber membranes are manufactured via electrospinning of eight different polymers: nylon 6 (PA6), polyimide (PI), poly(3-hydroxybuty-rate-co-3-hydroxyvalerate (PHBV), poly(l-lactide) (PLLA), polycaprolactone (PCL), and polystyrene (PS), and two molecular weights poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) (PVB). Further, their morphology is examined through scanning electron microscopy (SEM), fibers, and pores diameter, wettability, and membrane thickness. Additionally, water vapor transmission rates (WVTR) are measured, and notably, skin hydration tests are conducted before and after using evening primrose oil-infused patches. The comparison and findings highlight the flexibility of electrospun patches, demonstrating their potential in maintaining skin hydration for 6 h and enhancing skin moisture, which are necessary in AD treatment. These insights, which focus on selecting the most effective performance patches, help improve skin moisture, leading to tailored treatments for AD, which can significantly impact the efforts to reduce healthcare costs and simplify skincare steps.
Access status: Open Access ,
Strength, water absorption, thermal and antimicrobial properties of a biopolymer composite wound dressing
(AGH University of Science and Technology Press, 2022) Chiosa Odili, Cletus; Sekunowo, Olatunde Israel; Ilomuanya, Margaret Okonawan; Gbenebor, Oluwashina Philips; Adeosun, Samson Oluropo
Conventional wound material allows bacterial invasions, trauma and discomfort associated with the changing of the dressing material, and the accumulation of body fluid for wounds with high exudate. However, there is a shift from conventional wound dressing materials to polymeric nanofibers due to their high surface area to volume ratio, high porosity, good pore size distribution, which allows for cell adhesion and proliferation. There is an urgent need to synthesis a biodegradable composite that is resistant to bacterial infection. In this study, an electrospun polylactide (PLA) composite suitable for wound dressing, with enhanced antimicrobial and mechanical properties, was produced. The neat PLA, PLA/CH (10 wt.%), PLA/CH (5 wt.%), PLA/CHS (10 wt.%), PLA/CHS (5 wt.%), PLA/CH (2.5 wt.%) /CHS (2.5 wt.%) and PLA/CH (5 wt.%)/CHS (5 wt.%), were electrospun using 0.14 g/ml solution. Results show that crystallinity (67.6%) of neat PLA declined by 3.8% on the addition of 2.5 wt.% chitin/chitosan with improved hydrophilicity of the composite. The tensile strength of neat PLA (0.3 MPa) increased (0.6 MPa) with 2.5 wt.% chitin/chitosan addition. The slight increase in the glass transition temperature from 75°C for neat PLA to 78°C of the composite fibre, showed improved ductility. The fibres showed little beads, hence suitable for wound dressing. The electrospun mats have good water absorption capacity and strong resistance against <i>Staphylococcus aureus</i>. Good performance was attained at 5 wt.% of chitin, chitosan and hybrid reinforcements. Therefore, a PLA/chitin/chitosan composite is recommended as a wound dressing material.
Access status: Restricted ,
Wpływ sposobu udostępnienia złoża gazu ziemnego na efektywność wydobycia gazu
(Data obrony: 2019-09-27) Mróz, Piotr
Wydział Wiertnictwa, Nafty i Gazu